The hotel is located in the heart of Old San Juan and is close to a number of historic sites. Guests staying at the Sheraton Old San Juan Hotel & Casino can also visit the beach and the various shops and eateries in the area. The hotel is just 8 miles from the airport, which is easily reachable by car. If guests do not have their own vehicles or rental cars, they can use public transportation to reach other areas. Some attractions are within walking distance of the Sheraton Old San Juan Hotel & Casino.

The guestrooms at the Sheraton Old San Juan Hotel & Casino feature modern amenities such as flat screen TVs, bathrooms, and air conditioning.

When staying at the hotel, guests will be able to dine at the onsite restaurant and relax in one of the two lounges. The hotel also has a swimming pool, a Jacuzzi, and a health club. Guests at the Sheraton Old San Juan Hotel & Casino will also be able to play at the onsite casino. A sky bridge connects the hotel to Isla Bonita.